1,2,3,4-四氢-2-甲基-6-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-异喹啉合成路线 (共 3 条)
反应条件
1: 8 h / 20 °C
2: H2 / PtO2 / ethanol / 24 h / 20 °C / 2280 Torr
View Scheme
参考文献
Wang, Qiuping; Lucien, Edlaine; Hashimoto, Akihiro; Pais, Godwin C. G.; Nelson, David M.; Song, Yongsheng; Thanassi, Jane A.; Marlor, Christopher W.; Thoma, Christy L.; Cheng, Jijun; Podos, Steven D.; Ou, Yangsi; Deshpande, Milind; Pucci, Michael J.; Buechter, Douglas D.; Bradbury, Barton J.; Wiles, Jason A.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 2 p. 199 - 210
反应条件
1: 54 percent / KOAc / PdCl2(dppf)*CH2Cl2 / dimethylformamide / 17 h / 80 °C
2: 8 h / 20 °C
3: H2 / PtO2 / ethanol / 24 h / 20 °C / 2280 Torr
View Scheme
参考文献
Wang, Qiuping; Lucien, Edlaine; Hashimoto, Akihiro; Pais, Godwin C. G.; Nelson, David M.; Song, Yongsheng; Thanassi, Jane A.; Marlor, Christopher W.; Thoma, Christy L.; Cheng, Jijun; Podos, Steven D.; Ou, Yangsi; Deshpande, Milind; Pucci, Michael J.; Buechter, Douglas D.; Bradbury, Barton J.; Wiles, Jason A.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 2 p. 199 - 210
反应条件
1: 54 percent / KOAc / PdCl2(dppf)*CH2Cl2 / dimethylformamide / 17 h / 80 °C
2: 8 h / 20 °C
3: H2 / PtO2 / ethanol / 24 h / 20 °C / 2280 Torr
View Scheme
参考文献
Wang, Qiuping; Lucien, Edlaine; Hashimoto, Akihiro; Pais, Godwin C. G.; Nelson, David M.; Song, Yongsheng; Thanassi, Jane A.; Marlor, Christopher W.; Thoma, Christy L.; Cheng, Jijun; Podos, Steven D.; Ou, Yangsi; Deshpande, Milind; Pucci, Michael J.; Buechter, Douglas D.; Bradbury, Barton J.; Wiles, Jason A.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 2 p. 199 - 210