1: 1-phenyl-3-phenyl-propyn-3-ol With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.166667 h; 2: ethyl bromoacetate in tetrahydrofuran; hexane T=-78 - 20°C;

potassium hydroxide in methanol 16 h;

1.1: 1.38 g / aq. KOH / methanol / 16 h 2.1: [2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium]*BF4 / CH2Cl2 / 0.5 h 2.2: 80 percent / (i-Pr)2NEt / CH2Cl2 / 2 h View Scheme