1: 86 percent / TMSN3 / SnCl4 / CH2Cl2 2: 1.) H2; 2.) DCC / 1.) PtO2 / 1.) acetone 3: 2.) Dowex 50W-X8 / 1.) NaOMe / 1.) MeOH 4: Dowex 50W-X8 / acetone 5: 1.) 1H-tetrazole; 2.) m-CPBA / 1.) CH2Cl2 6: 64 percent / H2 / Pd-C / aq. ethanol 7: TFA / H2O / 24 h / Ambient temperature View Scheme

1: Dowex 50W-X8 / acetone 2: 1.) 1H-tetrazole; 2.) m-CPBA / 1.) CH2Cl2 3: 64 percent / H2 / Pd-C / aq. ethanol 4: TFA / H2O / 24 h / Ambient temperature View Scheme

1: 1.) 1H-tetrazole; 2.) m-CPBA / 1.) CH2Cl2 2: 64 percent / H2 / Pd-C / aq. ethanol 3: TFA / H2O / 24 h / Ambient temperature View Scheme

1: 64 percent / H2 / Pd-C / aq. ethanol 2: TFA / H2O / 24 h / Ambient temperature View Scheme

1: 1.) H2; 2.) DCC / 1.) PtO2 / 1.) acetone 2: 2.) Dowex 50W-X8 / 1.) NaOMe / 1.) MeOH 3: Dowex 50W-X8 / acetone 4: 1.) 1H-tetrazole; 2.) m-CPBA / 1.) CH2Cl2 5: 64 percent / H2 / Pd-C / aq. ethanol 6: TFA / H2O / 24 h / Ambient temperature View Scheme

trifluoroacetic acid in water 24 h; Ambient temperature;