in hexane; dichloromethane 0.75 h; Heating;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4153970', constants.ctx, '0')">sodium hydrogencarbonate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />22.5&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 1.) phenyllithium / 1a) THF, -78 deg C, 15min; 1b) up to room temp.; 1c) room. temp., 45min; 2.) 2h, -78 deg C to room temp.<br />2: 90 percent / activated MnO₂ / CH₂Cl₂ / 16 h / Heating<br />3: 100 percent / N-bromosuccinimide / benzoyl peroxide / CCl₄ / 2.5 h / Heating<br />4: 96 percent / H₂O, sodium bicarbonate / tetrahydrofuran / 22.5 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 1.) n-butyllithium / 1.) THF, 1h, -78 deg C to 0 deg C, 2.) -78 deg C to room temp.<br />2: 1.) phenyllithium / 1a) THF, -78 deg C, 15min; 1b) up to room temp.; 1c) room. temp., 45min; 2.) 2h, -78 deg C to room temp.<br />3: 90 percent / activated MnO₂ / CH₂Cl₂ / 16 h / Heating<br />4: 100 percent / N-bromosuccinimide / benzoyl peroxide / CCl₄ / 2.5 h / Heating<br />5: 96 percent / H₂O, sodium bicarbonate / tetrahydrofuran / 22.5 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 1.) n-butyllithium / 1.) THF, 1h, -78 deg C to 0 deg C, 2.) -78 deg C to room temp.<br />2: 1.) phenyllithium / 1a) THF, -78 deg C, 15min; 1b) up to room temp.; 1c) room. temp., 45min; 2.) 2h, -78 deg C to room temp.<br />3: 90 percent / activated MnO₂ / CH₂Cl₂ / 16 h / Heating<br />4: 100 percent / N-bromosuccinimide / benzoyl peroxide / CCl₄ / 2.5 h / Heating<br />5: 96 percent / H₂O, sodium bicarbonate / tetrahydrofuran / 22.5 h<br /> <br /> &nbsp;