双(2,2,2-三氟乙基)亚磷酸酯合成路线 （共 12 条）
反应条件
1: Bis(2,2,2-trifluoroethyl) phosphonate With sodium hydride in tetrahydrofuran
T=20°C; 0.5 h;
2: maleic acid dimethyl ester in tetrahydrofuran
0.5 h;
3: benzaldehyde in tetrahydrofuran
3 h;
参考文献
Shen, Yanchang; Zhang, Yuming
Heteroatom Chemistry, 2003 , vol. 14, # 3 p. 276 - 279
反应条件
1: Bis(2,2,2-trifluoroethyl) phosphonate With sodium hydride in tetrahydrofuran
T=-42°C; Metallation;
2: methyl (R,S)-2-bromopropionate in tetrahydrofuran
T=20°C; Michaelis-Becker reaction;
参考文献
Ciszewski, Gregory M.; Jackson, John A.
Organic Preparations and Procedures International, 1999 , vol. 31, # 2 p. 240 - 243
