4-甲氧基-2-甲基-联苯合成路线 （共 109 条）
反应条件
potassium fluoride; (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; bis(dibenzylideneacetone)-palladium(0) in toluene
T=80°C; Suzuki coupling; 72 h;
参考文献
Tang, Yi-Qiang; Lu, Jian-Mei; Shao, Li-Xiong
Journal of Organometallic Chemistry, 2011 , vol. 696, # 23 p. 3741 - 3744
反应条件
potassium carbonate; [PS-PEG-adppp-Pd(η3-C3H5)]Cl in water
T=50°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Ye, Yue-Mei; Wang, Bin-Bin; Ma, Dan; Shao, Li-Xiong; Lu, Jian-Mei
Catalysis Letters, 2010 , vol. 139, # 3-4 p. 141 - 144
反应条件
NHC-Pd(II)-Im; potassium tert-butylate in water
T=80°C; Suzuki-Miyaura coupling; 24 h;
参考文献
Tang, Yi-Qiang; Lu, Jian-Mei; Shao, Li-Xiong
Journal of Organometallic Chemistry, 2011 , vol. 696, # 23 p. 3741 - 3744
反应条件
potassium fluoride; tris(dibenzylideneacetone)dipalladium (0); tri-tert-butyl phosphine in tetrahydrofuran
T=20°C; Suzuki cross-coupling; 12 h;
参考文献
Littke, Adam F.; Dai, Chaoyang; Fu, Gregory C.
Journal of the American Chemical Society, 2000 , vol. 122, # 17 p. 4020 - 4028
反应条件
lithium chloride in tetrahydrofuran; toluene
T=110°C; 48 h; Inert atmosphere;
参考文献
Shirakawa, Eiji; Okura, Keisho; Uchiyama, Nanase; Murakami, Takuya; Hayashi, Tamio
Chemistry Letters, 2014 , vol. 43, # 6 p. 922 - 924
反应条件
bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=20°C; Suzuki-Miyaura coupling; 8 h;
参考文献
Tang, Zhen-Yu; Hu, Qiao-Sheng
Journal of the American Chemical Society, 2004 , vol. 126, # 10 p. 3058 - 3059
反应条件
C35H31BrN4NiP in tetrahydrofuran
T=70°C; 17 h; Schlenk techniqueInert atmosphere;
参考文献
Guo, Wang-Jun; Wang, Zhong-Xia
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 1054 - 1061
反应条件
1: 2-methylphenylmagnesium chloride With zinc(II) chloride in tetrahydrofuran
T=20°C; 0.333333 h;
2: 1-methoxy-4-chlorobenzene With Pd0(tris(tert-butyl)phosphine)2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=100°C; Negishi reaction; 24 h; Further stages.;
参考文献
Dai; Fu
Journal of the American Chemical Society, 2001 , vol. 123, # 12 p. 2719 - 2724
反应条件
bis(η3-allyl-μ-chloropalladium(II)); triphenyl-arsane; caesium carbonate in 1,4-dioxane
T=90°C; 24 h;
参考文献
Denmark, Scott E.; Ober, Michael H.
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1703 - 1714
反应条件
C31H26N6O4Pd; potassium carbonate in water
T=100°C; Suzuki-Miyaura coupling; 3 h;
参考文献
Li, Liuyi; Wang, Jinyun; Zhou, Chunshan; Wang, Ruihu; Hong, Maochun
Green Chemistry, 2011 , vol. 13, # 8 p. 2071 - 2077
