4-甲氧基-2-甲基-联苯合成路线 （共 109 条）
参考文献
Yale University
Patent: US6562989 B2, 2003 ;
反应条件
1: o-tolyltris(2-propoxy)titanium With N-(diphenylphosphino)-2-phenyl-1H-indole; palladium diacetate in toluene
0.0833333 h; Inert atmosphere;
2: 1-bromo-4-methoxy-benzene in toluene
T=90°C; 1 h; Inert atmosphere;
参考文献
Lee, Hang Wai; Lam, Fuk Loi; So, Chau Ming; Lau, Chak Po; Chan, Albert S. C.; Kwong, Fuk Yee
Angewandte Chemie, International Edition, 2009 , vol. 48, # 40 p. 7436 - 7439
Angewandte Chemie, 2009 , vol. 121, # 40 p. 7572 - 7575
反应条件
1: o-tolyltris(2-propoxy)titanium With N-methyl-2-phenyl-3-(dicyclohexylphosphino)-1H-indole; palladium diacetate in toluene
0.0833333 h; Inert atmosphere;
2: 1-methoxy-4-chlorobenzene in toluene
T=110°C; 16 h; Inert atmosphere;
参考文献
Lee, Hang Wai; Lam, Fuk Loi; So, Chau Ming; Lau, Chak Po; Chan, Albert S. C.; Kwong, Fuk Yee
Angewandte Chemie, International Edition, 2009 , vol. 48, # 40 p. 7436 - 7439
Angewandte Chemie, 2009 , vol. 121, # 40 p. 7572 - 7575
反应条件
sodium amalgam in methanol
2.08333 h; Inert atmosphereReflux;
参考文献
Chang, Meng-Yang; Chan, Chieh-Kai; Wu, Ming-Hao
Tetrahedron, 2013 , vol. 69, # 37 p. 7916 - 7924
反应条件
potassium carbonate; palladium diacetate in water; acetone
T=65°C; 16 h;
参考文献
Wallow, Thomas I.; Novak, Bruce M.
Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 5034 - 5037
反应条件
potassium carbonate; palladium diacetate in water; acetone
T=65°C; 0.67 h;
参考文献
Wallow, Thomas I.; Novak, Bruce M.
Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 5034 - 5037
反应条件
potassium carbonate; palladium diacetate in water; acetone
T=65°C; 0.666667 h;
参考文献
Wallow, Thomas I.; Novak, Bruce M.
Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 5034 - 5037
反应条件
cesium fluoride; tri-cyclo-hexyl-phosphine; palladium diacetate in tetrahydrofuran
T=55°C; Suzuki coupling; 16 h;
参考文献
Rostovtsev, Vsevolod V.; Bryman, Lois M.; Junk, Christopher P.; Harmer, Mark A.; Carcani, Liane G.
Journal of Organic Chemistry, 2008 , vol. 73, # 2 p. 711 - 714
反应条件
potassium phosphate; NiCl2((PPh3)P)2 in toluene
T=110°C; 24 h; Inert atmosphere;
参考文献
Quasdorf, Kyle W.; Tian, Xia; Garg, Neil K.
Journal of the American Chemical Society, 2008 , vol. 130, # 44 p. 14422 - 14423
反应条件
Pd0(tris(tert-butyl)phosphine)2 in toluene
T=90°C; Inert atmosphere;
参考文献
Denmark, Scott E.; Smith, Russell C.; Chang, Wen-Tau T.; Muhuhi, Joseck M.
Journal of the American Chemical Society, 2009 , vol. 131, # 8 p. 3104 - 3118
