4-甲氧基-2-甲基-联苯合成路线 （共 109 条）
反应条件
Ni(PCy3)2Cl2; tri-cyclo-hexyl-phosphine in diethyl ether
T=20°C; Kumada coupling; 2 h; Inert atmosphere;
参考文献
Guan, Bing-Tao; Lu, Xing-Yu; Zheng, Yang; Yu, Da-Gang; Wu, Tong; Li, Kun-N; Li, Bi-Jie; Shi, Zhang-Jie
Organic Letters, 2010 , vol. 12, # 2 p. 396 - 399
反应条件
potassium phosphate; N,N'-bis-[2,4,6-tri(3,3,3-trifluoropropyl)phenyl]-4,5-dihydroimidazolium chloride; palladium diacetate in tetrahydrofuran; water
T=20°C; Suzuki-Miyaura cross-coupling; 12 h; Inert atmosphere;
参考文献
Liu, Taoping; Zhao, Xiaoming; Shen, Qilong; Lu, Long
Tetrahedron, 2012 , vol. 68, # 32 p. 6535 - 6547
反应条件
palladium diacetate; SIDip*HCl in 1,4-dioxane
T=100°C; P=760 Torr; 5 h;
参考文献
Andrus, Merritt B.; Ma, Yudao; Zang, Yunfu; Song, Chun
Tetrahedron Letters, 2002 , vol. 43, # 50 p. 9137 - 9140
反应条件
bis-triphenylphosphine-palladium(II) chloride; cesium fluoride in N,N-dimethyl-formamide
T=80°C; Suzuki-Miyaura cross-coupling; 2 h; Inert atmosphere;
参考文献
PraveenGanesh, Nageswaran; Chavant, Pierre Yves
European Journal of Organic Chemistry, 2008 , # 27 p. 4690 - 4696
反应条件
bis-triphenylphosphine-palladium(II) chloride; cesium fluoride in N,N-dimethyl-formamide
T=80°C; Suzuki-Miyaura cross-coupling; 2 h; Inert atmosphere;
参考文献
PraveenGanesh, Nageswaran; Chavant, Pierre Yves
European Journal of Organic Chemistry, 2008 , # 27 p. 4690 - 4696
反应条件
[(P{(NC5H10)(C6H11)2})2Pd(Cl)2] in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=100°C; Negishi cross-coupling reaction; 0.0833333 h; In air;
参考文献
Bolliger, Jeanne L.; Frech, Christian M.
Chemistry - A European Journal, 2010 , vol. 16, # 36 p. 11072 - 11081
反应条件
sodium hydroxide; Pd(NH3)2Cl2 in water
T=120°C; Hiyama coupling; 48 h;
参考文献
Chen, Shao-Nung; Wu, Wei-Yi; Tsai, Fu-Yu
Tetrahedron, 2008 , vol. 64, # 35 p. 8164 - 8168
反应条件
Ni(PCy3)2Cl2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=90°C; Negishi coupling reaction; 8 h; Inert atmosphere;
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide
T=90°C; 2 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
反应条件
catalyst 1 (aliphatic, phosphine based pincer complex of palladium) in 1,4-dioxane; 1-methyl-pyrrolidin-2-one
T=100°C; Negishi cross-coupling reaction; 1 h;
参考文献
Gerber, Roman; Blacque, Olivier; Frech, Christian M.
Dalton Transactions, 2011 , vol. 40, # 48 p. 12939 - 12941
