4-甲氧基-2-甲基-联苯合成路线 （共 109 条）
反应条件
1: para-iodoanisole With [PdCl2(1,3-bis(diphenylphosphino)propane)]; tBuCH2CH2B(H)NiPr2; triethylamine; potassium iodide in toluene
T=110°C; Suzuki coupling; 1 h; Inert atmosphere;
2: 1-iodo-2-methylbenzene With caesium carbonate in ethanol; water; toluene
T=90°C; Suzuki coupling; 15 h; Inert atmosphere;
参考文献
Marciasini, Ludovic; Richy, Nicolas; Vaultier, Michel; Pucheault, Mathieu
Chemical Communications, 2012 , vol. 48, # 10 p. 1553 - 1555
反应条件
C32H26ClN2NiOP in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=85°C; 12 h; Inert atmosphere;
参考文献
Zhang, Xue-Qi; Wang, Zhong-Xia
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3658 - 3663
反应条件
potassium phosphate; 1,1'-bis(diphenylphosphanyl)ferrocenenickel(II) chloride in toluene
T=110°C; Suzuki-Miyaura Coupling; 24 h; Schlenk technique;
参考文献
Li, Xiao-Jian; Zhang, Jin-Ling; Geng, Yu; Jin, Zhong
Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 5078 - 5084
反应条件
potassium phosphate; 1,1'-bis(diphenylphosphanyl)ferrocenenickel(II) chloride in toluene
T=110°C; Suzuki-Miyaura Coupling; 24 h; Schlenk technique;
参考文献
Li, Xiao-Jian; Zhang, Jin-Ling; Geng, Yu; Jin, Zhong
Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 5078 - 5084
反应条件
triphenyl-arsane; lithium chloride; tris-(dibenzylideneacetone)dipalladium(0) in various solvent(s)
T=80°C; Rate constant;
参考文献
Farina, Vittorio; Krishnan, Bala; Marshall, Daniel R.; Roth, Gregory P.
Journal of Organic Chemistry, 1993 , vol. 58, # 20 p. 5434 - 5444
反应条件
1.1: BuLi / diethyl ether; hexane / 1 h / -78 °C
1.2: 63 percent / diethyl ether; hexane / 13 h / 20 °C
2.1: 67 percent / Ag2O / Pd(PPh3)4 / tetrahydrofuran / 36 h / 60 °C
View Scheme
参考文献
Hirabayashi, Kazunori; Kawashima, Jun; Nishihara, Yasushi; Mori, Atsunori; Hiyama, Tamejiro
Organic Letters, 1999 , vol. 1, # 2 p. 299 - 301
反应条件
1.1: BuLi / diethyl ether; hexane / 1 h / -78 °C
1.2: 81 percent / diethyl ether; hexane / 13 h / 20 °C
2.1: 30 percent / Ag2O / Pd(PPh3)4 / tetrahydrofuran / 36 h / 60 °C
View Scheme
参考文献
Hirabayashi, Kazunori; Kawashima, Jun; Nishihara, Yasushi; Mori, Atsunori; Hiyama, Tamejiro
Organic Letters, 1999 , vol. 1, # 2 p. 299 - 301
反应条件
C68H72Cl2N6NiP2 in diethyl ether
T=25°C; Kumada coupling reaction; 12 h; Inert atmosphere;
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Chemistry - A European Journal, 2010 , vol. 16, # 34 p. 10332 - 10336
反应条件
C68H72Cl2N6NiP2 in diethyl ether
T=25°C; Kumada coupling reaction; 12 h; Inert atmosphere;
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Chemistry - A European Journal, 2010 , vol. 16, # 34 p. 10332 - 10336
反应条件
bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=25°C; 24 h; Inert atmosphere;
参考文献
Leowanawat, Pawaret; Zhang, Na; Resmerita, Ana-Maria; Rosen, Brad M.; Percec, Virgil
Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 9946 - 9955
