4-甲氧基-2-甲基-联苯合成路线 （共 109 条）
反应条件
palladium diacetate; potassium carbonate in methanol
T=60°C; Suzuki Coupling; Inert atmosphere;
参考文献
Liu, Jin-Biao; Yan, Hui; Chen, Hui-Xuan; Luo, Yu; Weng, Jiang; Lu, Gui
Chemical Communications, 2013 , vol. 49, # 46 p. 5268 - 5270
反应条件
1: 4-fluoromethoxybenzene; 2-methylbenzene zinc chloride With Ni(PCy3)2Cl2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=25 - 100°C; 10 h; Schlenk techniqueInert atmosphere;
2: 2-methylbenzene zinc chloride in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=100°C; 10 h; Inert atmosphereSchlenk technique;
参考文献
Zhu, Feng; Wang, Zhong-Xia
Journal of Organic Chemistry, 2014 , vol. 79, # 10 p. 4285 - 4292
反应条件
palladium diacetate; caesium carbonate; tri-cyclo-hexyl-phosphine in o-xylene
8 h; Heating;
参考文献
Terao, Yoshito; Wakui, Hiroyuki; Nomoto, Michiyo; Satoh, Tetsuya; Miura, Masahiro; Nomura, Masakatsu
Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5236 - 5243
反应条件
anhydrous dipotassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane
T=100 - 110°C; Suzuki-Miyaura coupling reaction; Inert atmosphere;
参考文献
Gao, Han; Li, You; Zhou, Yi-Guo; Han, Fu-She; Lin, Ying-Jie
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 2-3 p. 309 - 314
反应条件
potassium phosphate; Ni(PCy3)2Cl2 in 1,4-dioxane
T=110°C; Suzuki-Miyaura coupling; 24 h; Inert atmosphere;
参考文献
Chen, Hu; Huang, Zhongbin; Hu, Xiaoming; Tang, Guo; Xu, Pengxiang; Zhao, Yufen; Cheng, Chien-Hong
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2338 - 2344
反应条件
Ni(PCy3)2Cl2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=90°C; Negishi coupling reaction; 8 h; Inert atmosphere;
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
T=100°C; Stille Cross Coupling; 90 h; Inert atmosphere;
参考文献
Martinez-Arranz, Sheila; Carrera, Nora; Albeniz, Ana C.; Espinet, Pablo; Vidal-Moya, Alejandro
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 18 p. 3551 - 3560
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate; palladium dichloride in N,N-dimethyl-formamide
T=185°C; 20 h; Inert atmosphere;
参考文献
Ortgies, Dirk H.; Barthelme, Alexandre; Aly, Sara; Desharnais, Brigitte; Rioux, Steven; Forgione, Pat
Synthesis (Germany), 2013 , vol. 45, # 5 art. no. SS-2012-M0902-OP, p. 694 - 702
反应条件
anhydrous dipotassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane
T=100 - 110°C; Suzuki-Miyaura coupling reaction; Inert atmosphere;
参考文献
Gao, Han; Li, You; Zhou, Yi-Guo; Han, Fu-She; Lin, Ying-Jie
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 2-3 p. 309 - 314
反应条件
2,2'-biquinoline; 10 Pd/C; cesium fluoride in 1-methyl-pyrrolidin-2-one
T=140°C; 24 h; Inert atmosphere;
参考文献
Monguchi, Yasunari; Hattori, Tomohiro; Miyamoto, Yasuhiro; Yanase, Takayoshi; Sawama, Yoshinari; Sajiki, Hironao
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2561 - 2567
