4-甲基-4,5,6,7-四氢噻吩并[3,2-c]吡啶合成路线 (共 2 条)
反应条件
hydrogenchloride; water in ethanol 4 h; Inert atmosphereReflux;
参考文献
Kitabatake, Michikazu; Hashimoto, Aki; Saitoh, Toshiaki; Sano, Takehiro; Mohri, Kunihiko; Horiguchi, Yoshie
Heterocycles, 2010 , vol. 81, # 8 p. 1903 - 1921
反应条件
1.1: titanium(IV) isopropylate / 2 h / 80 °C / Inert atmosphere 2.1: acetic anhydride 2.2: 0 - 70 °C / Inert atmosphere 2.3: 1.5 h / 70 °C / Inert atmosphere 3.1: hydrogenchloride; water / ethanol / 4 h / Inert atmosphere; Reflux View Scheme
参考文献
Heterocycles, , vol. 81, # 8 p. 1903 - 1921