N-[1-(4-溴苯)乙基]乙酰胺合成路线 （共 6 条）
反应条件
triethylamine in dichloromethane
T=20°C; 0.5 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2007/107539 A1, 2007 ;
Location in patent: Page/Page column 95-96 ;
反应条件
triethylamine in dichloromethane
T=20°C; 12 h;
参考文献
CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; GAGNON, Alexandre; HARMANGE, Jean-christophe; NAVESCHUK, Christopher, G.
Patent: WO2013/75084 A1, 2013 ;
Location in patent: Paragraph 00221; 00222 ;
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; C34H27F4NP2 in dichloromethane
T=20°C; P=7600.51 Torr; 24 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Qiu, Min; Hu, Xiang-Ping; Huang, Jia-Di; Wang, Dao-Yong; Deng, Jun; Yu, Sai-Bo; Duan, Zheng-Chao; Zheng, Zhuo
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 17 p. 2683 - 2689
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; C48H42F12N2P2; hydrogen in dichloromethane; toluene
T=5°C; P=7500.75 Torr; Inert atmosphere; optical yield given as percent ee;
参考文献
Wang, Chun-Jiang; Gao, Feng; Liang, Gang
Organic Letters, 2008 , vol. 10, # 21 p. 4711 - 4714
反应条件
2,4-dinitrobenzenesulfonic acid hydrate
T=80°C; Ritter reaction; 30 h;
参考文献
Sanz, Roberto; Martinez, Alberto; Guilarte, Veronica; Alvarez-Gutierrez, Julia M.; Rodriguez, Felix
European Journal of Organic Chemistry, 2007 , # 28 p. 4642 - 4645
反应条件
acetamide; styrene; N-acetylacetamide; tetraethylammonium bromide in acetonitrile
electrolysis;
参考文献
Knittel, Dierk
Monatshefte fuer Chemie, 1984 , vol. 115, p. 523 - 532
