2-氨基-1-吡啶-4-基-乙醇合成路线 （共 8 条）
反应条件
hydrogenchloride; platinum Hydrogenation;
参考文献
Burrus; Powell
Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469
反应条件
ammonia in methanol
T=20°C; 120 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2006/113837 A2, 2006 ;
Location in patent: Page/Page column 125 ;
WO 2006/113837 A2
反应条件
10 Pd/C; hydrogen in methanol
T=20°C; 12 h;
参考文献
Bhabak, Krishna P.; Arenz, Christoph
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 20 p. 6162 - 6170
反应条件
hydrogenchloride; palladium
Hydrogenation;
参考文献
Burrus; Powell
Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469
反应条件
1: sodium ethylate
2: aqueous NaOH; NaNO2
3: ethanol; SnCl2+2 H2O; concentrated aqueous HCl
4: palladium; aqueous HCl / Hydrogenation
View Scheme
参考文献
Burrus; Powell
Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469
反应条件
1: ethanol; SnCl2+2 H2O; concentrated aqueous HCl
2: palladium; aqueous HCl / Hydrogenation
View Scheme
参考文献
Burrus; Powell
Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469
反应条件
1: aqueous NaOH; NaNO2
2: ethanol; SnCl2+2 H2O; concentrated aqueous HCl
3: palladium; aqueous HCl / Hydrogenation
View Scheme
参考文献
Burrus; Powell
Journal of the American Chemical Society, 1945 , vol. 67, p. 1468,1469
反应条件
1: triethylamine / 20 °C / |Inert atmosphere
2: 10 Pd/C; hydrogen / methanol / 12 h / 20 °C
View Scheme
参考文献
Bhabak, Krishna P.; Arenz, Christoph
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 20 p. 6162 - 6170
