1,3-双(对氯苄基)脲合成路线 （共 15 条）
反应条件
hydrogenchloride T=150°C; im Rohr;
参考文献
Curtius
Journal fuer Praktische Chemie (Leipzig), 1914 , vol. <2> 89, p. 500,512
Journal fuer Praktische Chemie (Leipzig), 1915 , vol. <2> 91, p. 7
反应条件
iodine; potassium carbonate; W(CO)6 in dichloromethane; water
T=70°C; Carbonylation; P=64604.3 Torr; 24 h;
参考文献
McCusker, Jennifer E.; Main, A. Denise; Johnson, Kirsten S.; Grasso, Cara A.; McElwee-White, Lisa
Journal of Organic Chemistry, 2000 , vol. 65, # 17 p. 5216 - 5222
反应条件
potassium carbonate in dimethyl sulfoxide
T=80°C; 0.5 h;
参考文献
Atanassova, I.A.; Petrov, J.S.; Mollov, N.M.
Synthetic Communications, 1989 , vol. 19, # 1, 2 p. 147 - 154
反应条件
in water
T=60°C; 8 h;
参考文献
Artuso, Emma; Degani, Iacopo; Fochi, Rita; Magistris, Claudio
Synthesis, 2007 , # 22 p. 3497 - 3506
反应条件
1: aq. NaNO2, HCO2H
2: H2O
View Scheme
参考文献
Johnston,T.P. et al.
J. Med. Chem., 1963 , vol. 6, p. 669 - 681
反应条件
1: CHCl3
2: aq. NaNO2, HCO2H
3: H2O
View Scheme
参考文献
Johnston,T.P. et al.
J. Med. Chem., 1963 , vol. 6, p. 669 - 681
反应条件
sodium tetrahydroborate in isopropyl alcohol
4 h; Heating;
参考文献
Bakibaev, A. A.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 11 p. 1771 - 1772
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 11 p. 1684 - 1685
反应条件
1: 84 percent / BF3*Et2O / 5 h / 40 °C
2: 77 percent / potassium carbonate / dimethylsulfoxide / 0.5 h / 80 °C
View Scheme
参考文献
Atanassova, I.A.; Petrov, J.S.; Mollov, N.M.
Synthetic Communications, 1989 , vol. 19, # 1, 2 p. 147 - 154
反应条件
in water
T=60°C; Title compound not separated from byproducts.;
参考文献
Artuso, Emma; Degani, Iacopo; Fochi, Rita; Magistris, Claudio
Synthesis, 2007 , # 22 p. 3497 - 3506
参考文献
Johnston,T.P. et al.
J. Med. Chem., 1963 , vol. 6, p. 669 - 681
