1,6-二溴-3-异喹啉胺合成路线 （共 4 条）
反应条件
dichloro-acetic acid; hydrogen bromide T=0 - 20°C;
参考文献
Frohn, Mike; Buerli, Roland W.; Riahi, Bobby; Hungate, Randall W.
Tetrahedron Letters, 2007 , vol. 48, # 3 p. 487 - 489
反应条件
1: 74 percent / NaH / dimethylsulfoxide / 90 °C 2: 93 percent / H2O / dimethylsulfoxide / 1 h / 115 °C 3: 59 percent / HBr; dichloroacetic acid / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 48, # 3 p. 487 - 489
反应条件
1: 93 percent / H2O / dimethylsulfoxide / 1 h / 115 °C 2: 59 percent / HBr; dichloroacetic acid / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 48, # 3 p. 487 - 489
反应条件
ammonium formate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=50°C; 96 h; Sealed tube;
参考文献
AMGEN INC.
Patent: WO2009/11880 A2, 2009 ;
Location in patent: Page/Page column 159-160 ;
WO 2009/011880 A2
