反应条件
1: 71 percent / lithium hydroxide monohydrate / methanol / 2 h / Ambient temperature
2: 71 percent / cuprous oxide, 1,10-phenanthroline / quinoline / 0.25 h / 170 °C
3: 64 percent / Lawesson's reagent / hexamethylphosphoric acid triamide / 2.45 h / 100 °C
4: 64 percent / ammonia / methanol / 18 h / 60 °C
5: 62 percent / boron trichloride / CH2Cl2 / 2.5 h / -78 °C
View Scheme
参考文献
Marquez, Victor E.; Lim, Mu-Ill; Treanor, Susan P.; Plowman, Jacqueline; Priest, Matthew A.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 9 p. 1687 - 1694
