5-氧代-4,5-二氢吡唑并[1,5-a]嘧啶-3-羧酸乙酯合成路线 （共 3 条）
反应条件
1: With caesium carbonate in N,N-dimethyl-formamide T=110°C; 15 h; 2: With acetic acid in N,N-dimethyl-formamide T=20°C; pH=4;
参考文献
ARRAY BIOPHARMA INC.; ALLEN, Shelley; ANDREWS, Steven S.; CONDROSKI, Kevin Ronald; HAAS, Julia; HUANG, Lily; JIANG, Yutong; KERCHER, Timothy; SEO, Jeongbeob
Patent: WO2011/6074 A1, 2011 ;
Location in patent: Page/Page column 70 ;
反应条件
acetic acid in ethanol T=140°C; 0.333333 h; Microwave irradiation;
参考文献
WO2012/34095 A1, ;
Page/Page column 68 ;
WO 2012/034095 A1
反应条件
trichlorophosphate 2 h; Reflux;
参考文献
ARRAY BIOPHARMA INC.; ALLEN, Shelley; ANDREWS, Steven S.; CONDROSKI, Kevin Ronald; HAAS, Julia; HUANG, Lily; JIANG, Yutong; KERCHER, Timothy; SEO, Jeongbeob
Patent: WO2011/6074 A1, 2011 ;
Location in patent: Page/Page column 70-71 ;
