1.1: (R)-COP-Cl / dichloromethane / 24 h / 20 °C 2.1: RuCl2(tricyclohexylphosphine)2(benzylidene) / |Reflux 3.1: sodium hydroxide / 12 h / 20 °C 4.1: 18 h / 20 °C 5.1: palladium 10 on activated carbon; tert.-butylhydroperoxide; potassium carbonate / dichloromethane; decane / 48 h / 40 °C 6.1: cerium(III) chloride heptahydrate / methanol / 0.5 h / 0 - 20 °C 6.2: 3 h / 0 °C View Scheme

dichloro bis(acetonitrile) palladium(II) in dichloromethane T=20°C; aza-Claisen rearrangement; 3 h;