Tilley, Jefferson W.; Levitan, Paul; Lind, Joan; Welton, Ann F.; Crowley, Herman J.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 185 - 193
Tilley, Jefferson W.; Levitan, Paul; Lind, Joan; Welton, Ann F.; Crowley, Herman J.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 185 - 193
Tilley, Jefferson W.; Levitan, Paul; Lind, Joan; Welton, Ann F.; Crowley, Herman J.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 185 - 193
Greenaway, Rebecca L.; Campbell, Craig D.; Holton, Oliver T.; Russell, C. Adam; Anderson, Edward A.
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14366 - 14370
ammonium chloride in tetrahydrofuran; methanol; water
To a stirred soln. of Me3SnCu*Me2S in THF (Ar, -78°C) was added sequentially a THF soln. of the 1-alkyne and CH3OH. The mixt. was stirred(10 min) and then at -63°C (12 h). Satd. aq. NH4Cl and ether were added; allowed to warm to room temp.; Aq. phase was extd. with ether. The org. exts. were washed (satd. aq. NH4Cl) and dried (MgSO4). Removal of the solvent; column chromy. (silica gel) followed by distillation. (E)-1-trimethylstannyl-1-alkene not isolated, detected by gas-liq. chromy..;
参考文献
Piers, Edward; Chong, J. Michael
Canadian Journal of Chemistry, 1988 , vol. 66, p. 1425 - 1429
