lithium tert-butylate in tert-butyl alcohol 27 h; Heating;

sodium hydride in tetrahydrofuran 72 h; Heating;

1: 88 percent / pyridine / 4 °C / overnight 2: 1.) NaH / 1.) THF, room temperature, 1 h; 2.) reflux, 72 h View Scheme

sodium hydride 1.) THF, room temperature, 1 h; 2.) reflux, 72 h; Yield given. Multistep reaction;

1: 1.) BH3*(CH3)2S, 2.) aq. NaOH, 30percent H2O2 / 1a.) THF, 0 deg C, 2 h, 1b.) room temperature, 2 h, 2.) water, 50 deg C, 1 h 2: 1.) NaH / 1.) THF, room temperature, 1 h, 2.) room temperature View Scheme