2-溴-1-(2,4-二氯苯基)-1-丙酮合成路线 (共 2 条)
反应条件
in diethyl ether; chloroform; ethyl acetate
参考文献
Imperial Chemical Industries PLC
Patent: US4871389 A1, 1989 ;
反应条件
1.1: iodine; magnesium / diethyl ether / Inert atmosphere
1.2: 6 h / Reflux
1.3: Heating
2.1: bromine / diethyl ether / 20 °C / Cooling with ice
View Scheme
参考文献
Lagoja, Irene; Pannecouque, Christophe; Griffioen, Gerard; Wera, Stefaan; Rojasdelaparra, Veronica Maria; Van Aerschot, Arthur
European Journal of Pharmaceutical Sciences, 2011 , vol. 43, # 5 p. 386 - 392