4-(4’-氟苄基)哌啶合成路线 （共 19 条）
反应条件
1: HCl 2: Et3SiH View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 44, p. S524 - S526
反应条件
1.1: tetrahydrofuran / 1 h / -78 °C 1.2: tetrahydrofuran / 18 h / -78 °C 2.1: H2 / 10 percent Pd/C / ethyl acetate / 24 h / 760 Torr 3.1: concd HCl / acetic acid / 4 h / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 12 p. 1377 - 1380
反应条件
1.1: bromine; FeCl3 / CH2Cl2 / 1.5 h / 18 °C 2.1: magnesium / tetrahydrofuran 2.2: tetrahydrofuran / 10 h / 20 °C 3.1: hydrogen; hydrochloric acid / Pd/C / methanol; H2O / 60 - 65 °C View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 48, # 6 p. 421 - 427
反应条件
phosphorus; hydrogen iodide in acetic acid 10 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 10 p. 3011 - 3022
反应条件
1: NaBH4 / ethanol / 0.5 h / Ambient temperature 2: phosphorous, 57percent aq. HI / acetic acid / 10 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 10 p. 3011 - 3022
反应条件
1.1: 9-BBN / tetrahydrofuran 1.2: Pd(dppf)Cl2; K2CO3 / tetrahydrofuran; dimethylformamide / Heating 2.1: 100 percent / HCl / dioxane; CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 5 p. 1375 - 1378
反应条件
1: AlCl3 2: HCl 3: Et3SiH View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 44, p. S524 - S526
反应条件
1: AlCl3 2: HCl 3: Et3SiH View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 44, p. S524 - S526
反应条件
triethylamine in ethanol
参考文献
Roger, G.; Liu, X.; Lagnel, B.; Besret, L.; Bramoulle, Y.; Coulon, C.; Ottaviani, M.; Valette, H.; Kassiou, M.; Bottlaender, M.; Dolle, F.
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, p. S32 - S32
