1: N'-((4-chlorophenyl)(cyclopropyl)methylene)-4-methylbenzenesulfonyl hydrazide With dichloro bis(acetonitrile) palladium(II); lithium tert-butylate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in 1,4-dioxane 0.0166667 h; Inert atmosphere; 2: 1-chloro-4-bromobenzene in 1,4-dioxane T=90°C; 2 h; Inert atmosphere;

acetic acid; triphenylphosphine; tetrakis(triphenylphosphine) palladium(0) in toluene T=80°C; 5 h;

1: With phosphonic acid,diphenyl ester in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: in tetrahydrofuran T=50°C; 5 h; Inert atmosphere;

1: in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: With phosphonic acid diethyl ester in tetrahydrofuran T=20°C; Inert atmosphere;

1.1: ethanol / |Reflux; |Inert atmosphere 2.1: dichloro bis(acetonitrile) palladium(II); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; lithium tert-butylate / 1,4-dioxane / 0.02 h / |Inert atmosphere 2.2: 2 h / 90 °C / |Inert atmosphere View Scheme

1: aq. HCl, AcOH 2: (i) MeI, (ii) aq. NaOH View Scheme

1: (i) Mg, EtBr, (ii) /BRN= 643345/ 2: aq. HCl, AcOH 3: (i) MeI, (ii) aq. NaOH View Scheme

(i) MeI, (ii) aq. NaOH; Multistep reaction;