6-(环己氧基)-3-吡啶甲胺合成路线 （共 2 条）
反应条件
borane-THF in tetrahydrofuran
T=0 - 20°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2007/28083 A2, 2007 ;
Location in patent: Page/Page column 76-77 ;
WO 2007/028083 A2
反应条件
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / 20 °C
1.2: 18 h / 20 °C
2.1: borane-THF / tetrahydrofuran / 1 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
BRISTOL-MYERS SQUIBB COMPANY; QIAO, Jennifer, X.; FINLAY, Heather; JIANG, Ji; LLOYD, John; HU, Carol Hui; PI, Zulan; TORA, George, O.; NEELS, James; HANGELAND, Jon, J.; FRIENDS, Todd, J.
Patent: WO2013/48928 A1, 2013 ;
