potassium hydroxide; 4-phenylbut-3-en-2-one; tris(triphenylphosphine)ruthenium(II) chloride in diethylene glycol dimethyl ether 20 h; Heating;

tert.-butylhydroperoxide; potassium tert-butylate in water T=80°C; 8 h;

Stage #1: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4386964', constants.ctx, '0')">cyclopropyl malonoyl peroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a> <br />T=40&deg;C;&nbsp;24&nbsp;h;&nbsp;<br />Stage #2: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '8128150', constants.ctx, '0')">sodium hydroxide</a> <br />T=60&deg;C;&nbsp;4&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: potassium <i>tert</i>-butylate / tetrahydrofuran / |Inert atmosphere<br />2: osmium(VIII) oxide; 4-methylmorpholine N-oxide / |Inert atmosphere<br /> <br /> &nbsp;