1,8-二氨基-3,6-二氧杂辛烷合成路线 （共 65 条）
参考文献
Shimaoka, Hideyuki; Kuramoto, Hiromitsu; Furukawa, Jun-Ichi; Miura, Yoshiaki; Kurogochi, Masaki; Kita, Yoko; Hinou, Hiroshi; Shinohara, Yasuro; Nishimura, Shin-Ichiro
Chemistry - A European Journal, 2007 , vol. 13, # 6 p. 1664 - 1673
反应条件
1: acetonitrile / 3 h
2: 72 percent / diisopropylethylamine / acetonitrile / 20 °C / pH 8 - 9
View Scheme
参考文献
Song, Aimin; Zhang, Jinhua; Lebrilla, Carlito B.; Lam, Kit S.
Journal of the American Chemical Society, 2003 , vol. 125, # 20 p. 6180 - 6188
反应条件
1: succinic acid anhydride; 2-[2-(2-aminoethoxy)ethoxy]-ethylamine in acetonitrile
3 h;
2: (9H-Fluoren-9-yl)-methyl chloroformate in water; acetonitrile
T=20°C; pH=7 - 8;
参考文献
Soriano, Aroa; Ventura, Ruben; Molero, Anabel; Hoen, Rob; Casado, Vicent; Corte, Antoni; Fanelli, Francesca; Albericio, Fernando; Lluis, Carmen; Franco, Rafael; Royo, Miriam
Journal of Medicinal Chemistry, 2009 , vol. 52, # 18 p. 5590 - 5602
反应条件
1: benzene
2: NaBH4, BF3*Et2O / tetrahydrofuran
View Scheme
参考文献
Buhleier,E. et al.
Chemische Berichte, 1979 , vol. 112, p. 546 - 558
反应条件
caesium carbonate in acetonitrile
168 h; Reflux;
参考文献
Gamage, Nipuni-Dhanesha H.; Mei, Yujiang; Garcia, Joel; Allen, Matthew J.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 47 p. 8923 - 8925
