7-羟基-4-(4-吡啶)香豆素合成路线 （共 3 条）
反应条件
sulfuric acid; trifluoroacetic acid T=20°C; 1 h;
参考文献
Leonetti, Francesco; Favia, Angelo; Rao, Angela; Aliano, Rosaria; Paluszcak, Anja; Hartmann, Rolf W.; Carotti, Angelo
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6792 - 6803
参考文献
Journal of Medicinal Chemistry, , vol. 7, p. 446 - 449
反应条件
1: 7-hydroxy-4-(pyridin-4-yl)-2H-chromen-2-one With sodium hydride in N,N-dimethyl-formamide
T=0°C; 0.333333 h;
2: methyl iodide With sodium hydride in N,N-dimethyl-formamide
T=0 - 20°C; 5 h;
参考文献
Leonetti, Francesco; Favia, Angelo; Rao, Angela; Aliano, Rosaria; Paluszcak, Anja; Hartmann, Rolf W.; Carotti, Angelo
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6792 - 6803
