异恶唑并[5,4-B]吡啶-3-胺合成路线 （共 5 条）
反应条件
1: methanecarbohydroxamic acid With potassium tert-butylate in N,N-dimethyl-formamide T=20°C; 0.5 h; 2: 2-fluoro-nicotinonitrile in N,N-dimethyl-formamide T=50°C; 5 h;
参考文献
US2010/234419 A1, ;
Page/Page column 15 ;
反应条件
hydroxylamine in ethanol T=5 - 20°C;
参考文献
Poreba, Krystyna; Wietrzyk, Joanna; Opolski, Adam
Acta Poloniae Pharmaceutica - Drug Research, 2003 , vol. 60, # 4 p. 293 - 301
反应条件
hydroxylamine hydrochloride; sodium formate in methanol T=0°C; 0.333333 h;
参考文献
Dunn, A. D.
Zeitschrift fuer Chemie (Stuttgart, Germany), 1987 , vol. 27, # 9 p. 337 - 338
反应条件
potassium hydroxide in diethyl ether 6 h; Heating;
参考文献
Poreba, Krystyna; Wietrzyk, Joanna; Opolski, Adam
Acta Poloniae Pharmaceutica - Drug Research, 2003 , vol. 60, # 4 p. 293 - 301
反应条件
potassium carbonate in tetrahydrofuran
Heating;
参考文献
Poreba, Krystyna; Wietrzyk, Joanna; Opolski, Adam
Acta Poloniae Pharmaceutica - Drug Research, 2003 , vol. 60, # 4 p. 293 - 301
