2-溴-N-(异噁唑-3-基)乙酰胺合成路线 (共 3 条)
反应条件
triethylamine in dichloromethane
T=0 - 20°C; 2 h; Inert atmosphere;
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281398 A1, 2013 ;
Location in patent: Paragraph 0556; 0557 ;
反应条件
triethylamine in diethyl ether
T=-40°C; 3.3 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2004/96800 A2, 2004 ;
Location in patent: Page 76 ;
WO 2004/096800 A2
反应条件
potassium carbonate in dichloromethane
参考文献
Bull, Richard James; Skidmore, Elizabeth Anne; Ford, Rhonan Lee; Mather, Andrew Nigel; Mete, Antonio
Patent: US2011/172237 A1, 2011 ;
Location in patent: Page/Page column 20 ;