1: 78 percent / 3 h / Temperature: from -20 deg C to room temp. 2: 70 percent / pyridine; CH2Cl2 / 3 h / 0 °C 3: 48 percent / hexamethylphosphoric acid triamide / 20 h / Ambient temperature 4: 1.) HF*Pyr, 2.) NH3 / 1.) THF, room temp., 2 days, 2.) methanol View Scheme

1: 70 percent / pyridine; CH2Cl2 / 3 h / 0 °C 2: 48 percent / hexamethylphosphoric acid triamide / 20 h / Ambient temperature 3: 1.) HF*Pyr, 2.) NH3 / 1.) THF, room temp., 2 days, 2.) methanol View Scheme

1: 48 percent / hexamethylphosphoric acid triamide / 20 h / Ambient temperature 2: 1.) HF*Pyr, 2.) NH3 / 1.) THF, room temp., 2 days, 2.) methanol View Scheme

ammonia; pyridine hydrogenfluoride 1.) THF, room temp., 2 days, 2.) methanol; Multistep reaction;