6-溴-4-乙基吡啶-3-胺合成路线 （共 3 条）
反应条件
acetic acid; sodium nitrite in water T=20°C; 24 h;
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Viraj B.; Woods, Keith; Luo, Yan; Liu, Xuesong; Guan, Ran; Klinghofer, Vered; Johnson, Eric F.; Stoll, Vincent S.; Mamo, Mulugeta; Li, Qun; Rosenberg, Saul H.; Giranda, Vincent L.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2441 - 2452
反应条件
hydrogen; nickel in tetrahydrofuran
18 h;
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Viraj B.; Woods, Keith; Luo, Yan; Liu, Xuesong; Guan, Ran; Klinghofer, Vered; Johnson, Eric F.; Stoll, Vincent S.; Mamo, Mulugeta; Li, Qun; Rosenberg, Saul H.; Giranda, Vincent L.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2441 - 2452
反应条件
1: 54 percent / hydrobromic acid; Br2 / 1.5 h / cooling
2: 90 percent / hydrogen / nickel / tetrahydrofuran / 18 h
View Scheme
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Viraj B.; Woods, Keith; Luo, Yan; Liu, Xuesong; Guan, Ran; Klinghofer, Vered; Johnson, Eric F.; Stoll, Vincent S.; Mamo, Mulugeta; Li, Qun; Rosenberg, Saul H.; Giranda, Vincent L.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2441 - 2452
