2,5-二甲氧基苯甲醛合成路线 （共 179 条）
反应条件
(i) HC(OEt)3, H3PO4, (ii) /BRN= 605351/, ZnCl2, AcOEt, (iii) aq. NaOAc, AcOH; Multistep reaction;
参考文献
Billman; Tonnis
Journal of pharmaceutical sciences, 1971 , vol. 60, # 8 p. 1188 - 1192
反应条件
boron tribromide in dichloromethane T=-78 - 0°C; 1 h;
参考文献
Li, Chaomin; Johnson, Richard P.; Porco Jr., John A.
Journal of the American Chemical Society, 2003 , vol. 125, # 17 p. 5095 - 5106
反应条件
1: in tetrahydrofuran T=0°C; Green chemistry; 2: With [bis(acetoxy)iodo]benzene T=0 - 20°C; Green chemistry;
参考文献
Sagara, Prateep Singh; Chebolu, Rajesh; Bahuguna, Ashish; Ravikumar
RSC Advances, 2014 , vol. 4, # 29 p. 15011 - 15013
反应条件
ammonium acetate; malonic acid in ethanol
参考文献
Queen's University at Kingston
Patent: US6306909 B1, 2001 ;
反应条件
ammonium acetate in ethanol 6 h; Heating;
参考文献
Tan; Weaver
Tetrahedron, 2002 , vol. 58, # 37 p. 7449 - 7461
参考文献
Dallemagne, Patrick; Rault, Sylvain; Pilo, Juan Carlos; Foloppe, Marie Paule; Robba, Max
Tetrahedron Letters, 1991 , vol. 32, # 44 p. 6327 - 6328
反应条件
1: 90 percent / NH4OAc / 7 h / 105 °C 2: 52 percent / H2, glacial AcOH / Raney Ni / 2 h / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 21 p. 3103 - 3112
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol
参考文献
Wenkert,E. et al.
Journal of Organic Chemistry, 1964 , vol. 29, p. 435 - 439
反应条件
1: sodium amalgam; spirits of wine 2: benzene; PCl5 3: water; alcohol / man verseift das Nitril mit alkoh. Kali View Scheme
参考文献
Baumann; Fraenkel
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1895 , vol. 20, p. 221
反应条件
ammonium acetate T=105°C; 7 h;
参考文献
Rosowsky, Andre; Mota, Clara E.; Wright, Joel E.; Freisheim, James H.; Heusner, James J.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 21 p. 3103 - 3112
