2,5-二甲氧基苯甲醛合成路线 （共 179 条）
反应条件
1: tetrahydrofuran / 1 h / Heating 2: PDC / CH2Cl2 / 48 h / Ambient temperature View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 9 p. 1051 - 1056
反应条件
sodium tetrahydroborate in methanol T=0 - 20°C;
参考文献
Tatsuta, Kuniaki; Tokishita, Sonoko; Fukuda, Tomohiro; Kano, Takaaki; Komiya, Tadaaki; Hosokawa, Seijiro
Tetrahedron Letters, 2011 , vol. 52, # 9 p. 983 - 986
反应条件
1: 1.) NaOH, 2.) 4N aq. HCl / 1.) H2O, methanol, -3 deg C, 15 min 2: LiAlH4 / tetrahydrofuran / 2 h / Heating View Scheme
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
反应条件
1: NaBH4 / methanol / Ambient temperature 2: SOCl2 / toluene / 0.08 h / Ambient temperature View Scheme
参考文献
Baumann; Fraenkel
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1895 , vol. 20, p. 221
反应条件
1: 90 percent / zinc iodide / 1 h / Ambient temperature 2: 54 percent / lithium aluminum hydride / diethyl ether / 1 h / Heating View Scheme
参考文献
Perez; Rosell; Mauleon; Carganico
Farmaco, 1991 , vol. 46, # 10 p. 1155 - 1166
反应条件
1: platinum; ethanol / Hydrogenation 2: pyridine; SOCl2 5: Raney nickel; ethanolic NH3 / 100 °C / 73550.8 Torr / Hydrogenation 6: HBr; water / anschl. mit K3Fe(CN)6 und NaHCO3 in H2O View Scheme
参考文献
Harley-Mason; Jackson
Journal of the Chemical Society, 1954 , p. 1165,1168
反应条件
1: Br2, SnCl4 2: KMnO4 View Scheme
参考文献
Simmons, Rebecca L.; Yu, Robert T.; Myers, Andrew G.
Journal of the American Chemical Society, 2011 , vol. 133, # 40 p. 15870 - 15873
反应条件
magnesium 1.) ether, reflux, 0.5 h, 2.) ether, reflux, 2 h; Yield given. Multistep reaction;
参考文献
Hartmann; Heindl; Schwarz; Schonenberger
Journal of Medicinal Chemistry, 1984 , vol. 27, # 7 p. 819 - 824
参考文献
Kraus, George A.; Li, Jun; Gordon, Mark; Jensen, Jan H.
Journal of Organic Chemistry, 1994 , vol. 59, # 8 p. 2219 - 2222
反应条件
sodium hydride in tetrahydrofuran T=50°C;
参考文献
Goulle, Veronique; Harriman, Anthony; Lehn, Jean-Marie
Journal of the Chemical Society, Chemical Communications, 1993 , # 12 p. 1034 - 1036
