2,5-二甲氧基苯甲醛合成路线 （共 179 条）
反应条件
1: anhydrous diethyl succinate With ethanol; sodium hydride in toluene T=40°C; deprotonation; 2: 2,5-dimethoxy-benzaldehyde With sodium acetate in acetic anhydride Condensation; Stobbe; Heating; 3: With hydrogenchloride in ethanol deacetylation; Heating;
参考文献
Couladouros, Elias A.; Strongilos, Alexandros T.
Tetrahedron Letters, 2000 , vol. 41, # 4 p. 535 - 538
反应条件
1: NaBH4 / ethanol / 0 °C 2: HCl / benzene 3: NaI / dimethylsulfoxide / 16 h / 90 °C View Scheme
参考文献
Harley-Mason; Jackson
Journal of the Chemical Society, 1954 , p. 1165,1168
反应条件
ammonium acetate in ethanol 6 h; Heating;
参考文献
Tan; Weaver
Tetrahedron, 2002 , vol. 58, # 37 p. 7449 - 7461
反应条件
potassium hydroxide; ethanol Behandeln des Reaktionsproduktes mit Salzsaeure;
参考文献
Solomonovici,A.; Blumberg,S.
Tetrahedron, 1966 , vol. 22, p. 2505 - 2509
参考文献
Kauffmann
Chemische Berichte, 1917 , vol. 50, p. 635
Chemische Berichte, 1919 , vol. 52, p. 1431
反应条件
1: sodium amalgam; spirits of wine 2: benzene; PCl5 3: water; alcohol / man verseift das Nitril mit alkoh. Kali 4: fuming hydriodic acid; phosphorus View Scheme
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 20, p. 221
反应条件
1: ethanol; toluene 2: H2 / 10 percent Pd/C / ethanol View Scheme
参考文献
Hayes, Jerome F.
Synlett, 1999 , # SPEC. ISS. p. 865 - 866
反应条件
potassium carbonate in methanol T=4°C; Horner-Wadsworth-Emmons reaction; 36 h;
参考文献
Barrett, Anthony G. M.; Hopkins, Brian T.; Love, Andrew C.; Tedeschi, Livio
Organic Letters, 2004 , vol. 6, # 5 p. 835 - 837
反应条件
1: 1.) MMPP 2: 1.) n-BuLi, TMEDA / 1.) THF, - 78 deg C 3: 86 percent / PCC, celite / CH2Cl2 4: 96 percent / p-TsOH / dioxane; H2O / 55 °C 5: 93 percent / K2CO3 / dimethylformamide / 70 °C View Scheme
参考文献
Capecchi, Tanya; De Koning, Charles B.; Michael, Joseph P.
Tetrahedron Letters, 1998 , vol. 39, # 30 p. 5429 - 5432
反应条件
in propionic acid 1.5 h; Heating; Yield given. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 707 - 710
