反应条件
1.1: bromine / acetic acid / 20 °C 2.1: magnesium / tetrahydrofuran / 2 h / |Inert atmosphere 2.2: -78 - 20 °C / |Inert atmosphere 3.1: tetrakis(triphenylphosphine) palladium(0) / ethylene glycol dimethyl ether / 0.5 h 3.2: |Reflux 4.1: boron tribromide / dichloromethane / 20 °C / |Reflux 5.1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C 6.1: Cl2Ni(1,2-bis(diphenylphosphino)ethane) / N,N-dimethyl-formamide / 0.5 h / 20 °C / |Heating 6.2: 40 h / 100 °C View Scheme
参考文献
Lim, Chung Woo; Tissot, Olivier; Mattison, Andrew; Hooper, Mark W.; Brown, John M.; Cowley, Andrew R.; Hulmes, David I.; Blacker, A. John
Organic Process Research and Development, 2003 , vol. 7, # 3 p. 379 - 384
