3,4-二甲氧基苯甲酸合成路线 （共 364 条）
反应条件
hydrogenchloride T=140 - 150°C; im geschlossenen Rohr;
参考文献
Chemische Berichte, , vol. 8, p. 512,1123
反应条件
T=140 - 150°C; im geschlossenen Rohr;
参考文献
Chemische Berichte, , vol. 8, p. 512,1123
反应条件
1: aqueous hydrobromic acid 2: hydrogen chloride 3: methanol. KOH-solution 4: aqueous KOH-solution View Scheme
参考文献
Lovecy; Robinson; Sugasawa
Journal of the Chemical Society, 1930 , p. 817,818
参考文献
Merck
Justus Liebigs Annalen der Chemie, 1858 , vol. 108, p. 60
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Tiemann; Matsmoto
Chemische Berichte, 1876 , vol. 9, p. 939
Chemische Berichte, 1878 , vol. 11, p. 131
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Zincke; Francke
Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 190
参考文献
Merck
Justus Liebigs Annalen der Chemie, 1858 , vol. 108, p. 60
Full Text Show Details
Tiemann; Matsmoto
Chemische Berichte, 1876 , vol. 9, p. 939
Chemische Berichte, 1878 , vol. 11, p. 131
Full Text Show Details
Zincke; Francke
Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 190
反应条件
[bis(acetoxy)iodo]benzene; sulfuric acid; iodine in acetic anhydride; acetic acid T=20°C;
参考文献
Tetrahedron Letters, , vol. 44, # 17 p. 3483 - 3486
反应条件
thionyl chloride in toluene
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP318235 A3, 1991 ;
反应条件
1: 3,4-dimethoxy-benzoic acid With n-butyllithium; 2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran; hexane T=-78 - 0°C; 2: methyl iodide in tetrahydrofuran; hexane T=0 - 40°C; 3 h; Further stages.;
参考文献
Tetrahedron, , vol. 64, # 46 p. 10552 - 10557
反应条件
1: 3,4-dimethoxy-benzoic acid With lithium diisopropyl amide in tetrahydrofuran T=66°C; 2 h; 2: methyl iodide in tetrahydrofuran T=40°C; Further stages.;
参考文献
Chau, Nguyet Trang Thanh; Nguyen, Thi Huu; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Tetrahedron, 2008 , vol. 64, # 46 p. 10552 - 10557
反应条件
1: 3,4-dimethoxy-benzoic acid With n-butyllithium; potassium tert-butylate in tetrahydrofuran; hexane T=-78 - -50°C; 2 h; 2: methyl iodide in tetrahydrofuran; hexane T=-78 - 20°C; Further stages.;
参考文献
Tetrahedron, , vol. 64, # 46 p. 10552 - 10557
