3,4-二甲氧基苯甲酸合成路线 （共 364 条）
反应条件
1: azidation 2: reduction View Scheme
参考文献
Heterocycles, , vol. 66, # 1 p. 659 - 666
反应条件
[bis(acetoxy)iodo]benzene; lithium iodide in 1,1,1,3,3,3-hexafluoroisopropanol T=20°C; Hunsdiecker type reaction;
参考文献
Hamamoto, Hiromi; Hattori, Sho; Takemaru, Kaori; Miki, Yasuyoshi
Synlett, 2011 , # 11 p. 1563 - 1566
反应条件
ammonium sulfate; sodium chloride; magnesium sulfate; calcium chloride T=30°C; pH=7.2;
参考文献
Bell, Stephen G.; Zhou, Ruimin; Yang, Wen; Tan, Adrian B. H.; Gentleman, Alexander S.; Wong, Luet-Lok; Zhou, Weihong
Chemistry - A European Journal, 2012 , vol. 18, # 52 p. 16677 - 16688
反应条件
hydrogenchloride T=140 - 150°C; im geschlossenen Rohr;
参考文献
Chemische Berichte, , vol. 8, p. 512,1123
反应条件
T=140 - 150°C; im geschlossenen Rohr;
参考文献
Chemische Berichte, , vol. 8, p. 512,1123
反应条件
1: (COCl)2; DMF / CH2Cl2 2: diethyl ether / 0 °C 3: aq. Ag2O / dioxane 4: (COCl)2; DMF / CH2Cl2 View Scheme
参考文献
Young, Jonathan R.; Huang, Song X.; Chen, Irene; Walsh, Thomas F.; DeVita, Robert J.; Wyvratt Jr., Matthew J.; Goulet, Mark T.; Ren, Ning; Lo, Jane; Yang, Yi Tien; Yudkovitz, Joel B.; Cheng, Kang; Smith, Roy G.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 15 p. 1723 - 1727
反应条件
1: hydrogen chloride 2: durch Nitrieren View Scheme
参考文献
Chen, Yurong; Feng, Man; Li, Shilei; Xu, Jingli; Ning, Hongyu; He, Yong; Wang, Xiao; Ding, Rui; Qi, Chuanmin
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 14 p. 4745 - 4749
反应条件
1.1: 89 percent / methanesulfonyl chloride; Et3N / tetrahydrofuran / 0 °C 2.1: Et3N / 0.08 h / Heating 2.2: 74 percent / KOH / methanol / 0.33 h / sonication View Scheme
参考文献
Daskiewicz, Jean-Baptiste; Depeint, Flore; Viornery, Lionel; Bayet, Christine; Comte-Sarrazin, Geraldine; Comte, Gilles; Gee, Jennifer M.; Johnson, Ian T.; Ndjoko, Karine; Hostettmann, Kurt; Barron, Denis
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2790 - 2804
反应条件
1: 98.3 percent / Na2CO3 / ethanol; H2O / 1.5 h / Heating 2: 89.2 percent / CH3CONH2, BF3*Et2O / xylene / 20 h / Heating View Scheme
参考文献
Huang, Wei; Pei, Jian; Chen, Bingzi; Pei, Weiwei; Ye, Xiulin
Tetrahedron, 1996 , vol. 52, # 30 p. 10131 - 10136
反应条件
1: With NbCl5 in dichloromethane 2: With ammonia in dichloromethane T=45 - 50°C; 3 h;
参考文献
Nery, Marcelo S.; Ribeiro, Renata P.; Lopes, Claudio C.; Lopes, Rosangela S. C.
Synthesis, 2003 , # 2 p. 272 - 276
