2-甲氧基-4-甲基苯酚合成路线 （共 145 条）
反应条件
2: aq. HCl / dioxane
3: (i) K2CO3, DMSO, (ii) NaBH4, aq. NaOH, dioxane
View Scheme
参考文献
Berndtson,L. et al.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1974 , vol. 28, p. 333 - 338
反应条件
1: 1) formylation, 2) K2CO3 / 2) DMF, 75 deg C, 4h
2: permanganate
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参考文献
Fletcher; Tarbell
Journal of the American Chemical Society, 1943 , vol. 65, p. 1431
反应条件
1: hydrogen bromide
2: glacial acetic acid; bromine
View Scheme
参考文献
Cousin
Annales de Chimie (Cachan, France), 1898 , vol. <7> 13, p. 497
反应条件
1.1: 95 percent / K2CO3 / acetone / 6 h / Heating
2.1: 90 percent / 24 h / 180 °C
3.1: 95 percent / KOH / methanol / 10 h / Heating
4.1: 96 percent / sodium hydroxyde / H2O / 1 h / Heating
5.1: NaHCO3; ozone / methanol; CH2Cl2 / 0.22 h / -70 °C
5.2: 80 percent / dimethyl sulfide / methanol; CH2Cl2 / 8 h / 20 °C
View Scheme
参考文献
Manske; Ledingham
Canadian Journal of Research, Section B: Chemical Sciences, 1944 , vol. 22, p. 115,123
反应条件
potassium carbonate
2) DMF, 75 deg C, 4h; Multistep reaction;
参考文献
Nicoletti, Teresa M.; Raston, Colin L.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 1 p. 133 - 138
反应条件
1: NaOH-solution
2: AlCl3; HCl / 40 °C / Behandlung des Reaktionsprodukts mit Eis und verd.Salzsaeure
3: aqueous potassium permanganate
View Scheme
参考文献
Perkin; Weizmann
Journal of the Chemical Society, 1906 , vol. 89, p. 1651
反应条件
sodium hydroxide; oxygen
T=45°C; P=63755.1 Torr; 1.5 h; var. temp., time, O2 pressure, conc. and amount of NaOH, different amounts of creosol; Product distributionMechanism;
参考文献
Fricko, Paul; Holocher-Ertl, Martin; Kratzl, Karl
Monatshefte fuer Chemie, 1980 , vol. 111, p. 1025 - 1042
反应条件
1: NaOH-solution
2: AlCl3; HCl / 40 °C / Behandlung des Reaktionsprodukts mit Eis und verd.Salzsaeure
3: methanol; sodium acetate; water
View Scheme
参考文献
Perkin; Weizmann
Journal of the Chemical Society, 1906 , vol. 89, p. 1651
反应条件
1: (i) Na, (ii) /BRN= 1751335/, PhNMe2
2: KOH / ethanol
View Scheme
参考文献
Hase,T.A. et al.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1977 , vol. 31, p. 501 - 504
反应条件
(i) Na, (ii) /BRN= 1699112/; Multistep reaction;
参考文献
Hase,T.A. et al.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1977 , vol. 31, p. 501 - 504
