(1R,2R)-(-)-反-1,2-环戊二醇合成路线 （共 22 条）
反应条件
1: 90 percent / pyridine / 4-(dimethylamino)pyridine / 12 h / Ambient temperature 2: lipase SAM II, phosphate buffer, pH 7.0 3: 47 percent / trimethylsilyl iodide / CHCl3 View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 110, # 5 p. 171 - 174
反应条件
water in acetonitrile T=37°C; Enzymatic reaction; optical yield given as percent eestereoselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 132, # 44 p. 15744 - 15751
反应条件
cyclic dioldehydrogenase from Rhodococcus sp. Moj-3449 in aq. buffer T=30°C; pH=8; 8 h; Enzymatic reaction; enantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 16 p. 3147 - 3153
反应条件
1: 95 percent / Et3N / diethyl ether / 24 h / 25 °C 2: NaI / acetonitrile / 6 h / 25 °C 3: MeOH / 6 h / 25 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 581, # 1-2 p. 116 - 121
反应条件
1.1: α-pinene; diisopinocampheylborane / tetrahydrofuran / 76 h / -25 °C 1.2: MeCHO / tetrahydrofuran / 24 h / 25 °C 1.3: 30 percent aq. H2O2; 3 M aq. NaOH / tetrahydrofuran / 6 h / 25 °C 2.1: 95 percent / Et3N / diethyl ether / 24 h / 25 °C 3.1: NaI / acetonitrile / 6 h / 25 °C 4.1: MeOH / 6 h / 25 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 581, # 1-2 p. 116 - 121
反应条件
1: NaI / acetonitrile / 6 h / 25 °C 2: MeOH / 6 h / 25 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 581, # 1-2 p. 116 - 121
反应条件
1: (+/-)-trans-cyclopentane-1,2-diol With (5aS,10bR)-9-nitro-2-phenyl-4,5a,6,10b-tetrahydroindeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-2-ium tetrafluoroborate; 4-(N,N-dimethylamino)benzoic acid; N,N,N',N'-tetra-methylnaphthalene-1,8-diamine in chloroform T=20°C; 0.166667 h; 2: 2-bromo-3-phenylpropanal in chloroform T=0°C; 14 h;
参考文献
Journal of the American Chemical Society, , vol. 135, # 31 p. 11485 - 11488
反应条件
C43H60N6O8; N-ethyl-N,N-diisopropylamine in toluene T=0°C; 24 h; Inert atmosphere; enantioselective reaction;
参考文献
Chemical Communications, , vol. 50, # 10 p. 1221 - 1223
反应条件
1: lipase SAM II, phosphate buffer, pH 7.0 2: 47 percent / trimethylsilyl iodide / CHCl3 View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 110, # 5 p. 171 - 174
反应条件
1: lipase SAM II, phosphate buffer pH 7.0 2: 60 percent / H2 / Pd/C View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 110, # 5 p. 171 - 174
