4-环戊烯-1,3-二酮合成路线 （共 39 条）
反应条件
boron trifluoride diethyl etherate in chloroform T=0°C; 1.5 h;
参考文献
Arnold, Leggy A.; Naasz, Robert; Minnaard, Adriaan J.; Feringa, Ben L.
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7244 - 7254
反应条件
chlorine in dichloromethane T=20°C; Chlorination; 120 h;
参考文献
Smeds; Franzen; Kronberg
Environmental Science and Technology, 1995 , vol. 29, # 7 p. 1839 - 1844
反应条件
sodium tetrahydroborate in methanol; diethyl ether
参考文献
Roberts, Stanley Michael; Santoro, Maria Gabriella; Anggard, Eric Emil
Patent: US2003/186941 A1, 2003 ;
反应条件
sodium tetrahydroborate; cerium(III) chloride 1.) r.t., 5 min, 2.) r.t., 5 h; Yield given. Multistep reaction;
参考文献
Khanapure, Subhash P.; Najafi, Nahid; Manna, Sukumar; Yang, Jing-Jing; Rokach, Joshua
Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7548 - 7551
反应条件
sodium tetrahydroborate; cerium(III) chloride in methanol
参考文献
Zuercher, William J.; Hashimoto, Masakazu; Grubbs, Robert H.
Journal of the American Chemical Society, 1996 , vol. 118, # 28 p. 6634 - 6640
反应条件
1: 4-methoxy-benzaldehyde With titanium (IV) isopropoxide in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: 2-cyclopentene-1,4-dione in tetrahydrofuran T=20°C; Knoevenagel condensation; 12 h; Inert atmosphere;
参考文献
Tichotova, Lucie; Matousova, Eliska; Spulak, Marcel; Kunes, Jiri; Votruba, Ivan; Buchta, Vladimir; Pour, Milan
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 20 p. 6062 - 6066
反应条件
1: benzaldehyde With titanium (IV) isopropoxide in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: 2-cyclopentene-1,4-dione in tetrahydrofuran T=20°C; Knoevenagel condensation; 12 h; Inert atmosphere;
参考文献
Tichotova, Lucie; Matousova, Eliska; Spulak, Marcel; Kunes, Jiri; Votruba, Ivan; Buchta, Vladimir; Pour, Milan
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 20 p. 6062 - 6066
反应条件
1: 4-chlorobenzaldehyde With titanium (IV) isopropoxide in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: 2-cyclopentene-1,4-dione in tetrahydrofuran T=20°C; Knoevenagel condensation; 12 h; Inert atmosphere;
参考文献
Tichotova, Lucie; Matousova, Eliska; Spulak, Marcel; Kunes, Jiri; Votruba, Ivan; Buchta, Vladimir; Pour, Milan
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 20 p. 6062 - 6066
反应条件
(i) H2, Raney-Ni, MeOH, (ii) /BRN= 1718733/, TsOH, benzene; Multistep reaction;
参考文献
Ruangsiyanand,C. et al.
Chemische Berichte, 1970 , vol. 103, p. 2403 - 2410
反应条件
1: H2 / Ni 2: TsOH View Scheme
参考文献
Mironov,V.A. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1973 , vol. 22, p. 570 - 573
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1973 , vol. 22, # 3 p. 596 - 599
