piperidine; 5-[(2S)-pyrrolidine-2-yl]-1H-tetrazole in chloroform T=20°C; Michael condensation; 72 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Wascholowski, Veit; Knudsen, Kristian Rahbek; Mitchell, Claire E. T.; Ley, Steven V.
Chemistry - A European Journal, 2008 , vol. 14, # 20 p. 6155 - 6165
hexafluoroisopropyl alcohol; (S)-N-(2-pyrrolidylmethyl)-N,N,N-trimethylammonium hydroxide in toluene amounts of chiral additive and 1,1,1,3,3,3-hexafluoro-2-propanol were varied; Product distribution;
