反应条件
trimethylaluminum; (1R,2R)-naphthylcyclohexylborondichloride in hexane; dichloromethane
byproducts: C10H12(CH3)O; addn. of AlMe3 (in hexane) to Co-complex (in CH2Cl2) at -20°C, addn. of ketone and catalyst (in CH2Cl2), stirring (under N2, -20°Cfor 36 h, then 20°C for 2 h); addn. of water and then CH2Cl2, drying (MgSO4), filtration, washing (CH2Cl2), solvent removal (reduced pressure), chromy. (SiO2, Et2O/hexane=1:1, then AcOEt), evapn. (vac.);
参考文献
Richardson, B. Matthew; Day, Cynthia S.; Welker, Mark E.
Journal of Organometallic Chemistry, 1999 , vol. 577, # 1 p. 120 - 125
