反应条件
1: NaBH4 / methanol / 1.) 0 deg C, 30 min, 2.) room temperature, 1 h
2: 30percent hydrogen peroxide / ethanol / 60 °C
3: CH2Cl2 / 1.) 0 deg C, 1 h, 2.) room temperature, 15 min
4: KCN, sodium acetate, pH 4.0 / CH2Cl2; H2O / 0.25 h
5: 50 percent / potassium tert-butoxide / tetrahydrofuran / 0.08 h / Ambient temperature
View Scheme
参考文献
Grierson,D.S.; Harris,M.; Husson,H.P.
Journal of the American Chemical Society, 1980 , vol. 102, p. 1064
