1: bromobenzene With lithium Inert atmosphere; 2: 1,6-dimethyl-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid ethyl ester in tetrahydrofuran T=-78°C; Inert atmosphere; chemoselective reaction;

1: PhZnPh With triphenylborane in toluene T=20°C; 0.5 h; Inert atmosphere; 2: 1,6-dimethyl-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid ethyl ester in toluene T=0°C; 48 h; Inert atmosphere;

in tetrahydrofuran T=-78°C;