3-氟-2-硝基-n-苯基苯胺合成路线 (共 2 条)
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
T=20°C; 16 h;
参考文献
Wyeth
Patent: US2007/72897 A1, 2007 ;
Location in patent: Page/Page column 86 ;
反应条件
1: hydrogen / palladium 10 on activated carbon / ethyl acetate / 7 h / 20 °C
2: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 2 h / 20 °C
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参考文献
Heald, Robert; Price, Stephen; Safina, Brian; Savy, Pascal Pierre Alexandre; Seward, Eileen Mary; Sutherlin, Daniel P.; Waszkowycz, Bohdan
Patent: US2012/202785 A1, 2012 ;