(6-氯吡嗪-2-基)乙酸合成路线 （共 2 条）
反应条件
1: With sodium hydroxide; water in tetrahydrofuran T=10°C; 24 h; Heating / reflux; 2: With hydrogenchloride in water T=20 - 25°C;
参考文献
WO2007/35153 A1, ;
Page/Page column 4-5 ;
反应条件
ammonia in water T=180°C; P=26252.6 Torr; 8 h; sealed vessel;
参考文献
Colbon, Paul J. J.; Foster, Alison C.; Giles, Melvyn E.; Patel, Zakariya; Singleton, John T.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1451 - 1456
