4-羟基-5-甲氧基-2-萘羧酸甲酯合成路线 （共 4 条）
反应条件
1: 3-Ethoxycarbonyl-4-(m-methoxyphenyl)-3-butensaeure; acetic anhydride With sodium acetate
3 h; Heating;
2: With sodium hydroxide in ethanol; water
T=20°C; 15 h;
3: methanol With sulfuric acid
17 h; Heating;
参考文献
Gabbutt, Christopher D.; Hepworth, John D.; Heron, B. Mark; Thomas, David A.; Kilner, Colin; Partington, Steven M.
Heterocycles, 2004 , vol. 63, # 3 p. 567 - 582
反应条件
1.1: sodium ethoxide / ethanol / 4 h / Heating
2.1: sodium acetate / 3 h / Heating
2.2: sodium hydroxide / ethanol; H2O / 15 h / 20 °C
2.3: H2SO4 / 17 h / Heating
View Scheme
参考文献
Gabbutt, Christopher D.; Hepworth, John D.; Heron, B. Mark; Thomas, David A.; Kilner, Colin; Partington, Steven M.
Heterocycles, 2004 , vol. 63, # 3 p. 567 - 582
反应条件
methanol; diethyl ether
参考文献
Schmid et al.
Helvetica Chimica Acta, 1950 , vol. 33, p. 595,596
参考文献
Schmid et al.
Helvetica Chimica Acta, 1950 , vol. 33, p. 595,596
