(1R,2R)-(-)-2-氨基环己醇合成路线 （共 31 条）
反应条件
ammonium hydroxide 5 deg C -> 25 deg C, overnight;
参考文献
Schlichter; Frahm
Archiv der Pharmazie, 1993 , vol. 326, # 7 p. 429 - 436
反应条件
di-isopropyl azodicarboxylate in toluene T=20°C; debenzylation; 336 h;
参考文献
Kroutil, Jiri; Trnka, Tomas; Cerny, Miloslav
Organic Letters, 2000 , vol. 2, # 12 p. 1681 - 1683
反应条件
1: With iodine in dichloromethane T=20°C; 2: With sodium hydroxide; dihydrogen peroxide in methanol; water T=20°C;
参考文献
Journal of the American Chemical Society, , vol. 130, # 27 p. 8669 - 8676
反应条件
hydrazine hydrate in water T=60°C; 3 h;
参考文献
Gupta, Pankaj; Rouf, Abdul; Shah, Bhahwal A.; Mukherjee, Debaraj; Taneja, Subhash C.
Synthetic Communications, 2013 , vol. 43, # 4 p. 505 - 519
反应条件
1: in dichloromethane 2: With iodine in dichloromethane T=20°C; 5 h; 3: With sodium hydroxide; dihydrogen peroxide in methanol; water
参考文献
Journal of the American Chemical Society, , vol. 130, # 27 p. 8669 - 8676
反应条件
1: 1.) toluene, 0 deg C to room temperature, 5 h; 2.) acetone, reflux, 6 h 2: 16 percent / 0.5 h / 130 °C 3: 36 percent / CH2Cl2 / 1 h / 10 °C / Irradiation 4: KOH / various solvent(s) / 0.08 h / 160 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1553 - 1561
反应条件
ethanol; ammonia; water
参考文献
Journal of the American Chemical Society, , vol. 42, p. 2620
反应条件
potassium hydroxide in various solvent(s) T=160°C; 0.0833333 h; Yield given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1553 - 1561
反应条件
1: aqueous hypochlorous acid 2: water; alcohol; ammonia View Scheme
参考文献
Journal of the American Chemical Society, , vol. 42, p. 2620
反应条件
1: nickel / Hydrogenation.unter Druck 2: phosphorus trichloride 3: aqueous hypochlorous acid 4: water; alcohol; ammonia View Scheme
参考文献
Journal of the American Chemical Society, , vol. 42, p. 2620
