N-(甲氧甲基)-N-(三甲基硅甲基)苄胺合成路线 （共 42 条）
反应条件
trifluoroacetic acid in toluene T=20°C; 2 h;
参考文献
US2006/19985 A1, ;
Page/Page column 17 ;
反应条件
1: With trifluoroacetic acid in dichloromethane T=0 - 20°C; 2: With sodium hydrogencarbonate in dichloromethane; water 3: With hydroxylamine in methanol; water T=20°C; 20 h;
参考文献
US2009/281118 A1, ;
Page/Page column 10 ;
US 20090281118 A1
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Laborde, Edgardo
Tetrahedron Letters, 1992 , vol. 33, # 44 p. 6607 - 6610
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Laborde, Edgardo
Tetrahedron Letters, 1992 , vol. 33, # 44 p. 6607 - 6610
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Laborde, Edgardo
Tetrahedron Letters, 1992 , vol. 33, # 44 p. 6607 - 6610
反应条件
1: 95 percent / TFA / CH2Cl2 2: 92 percent / NaOH / methanol View Scheme
参考文献
Fukui, Hideto; Shibata, Tetsuo; Naito, Takanobu; Nakano, Jun; Maejima, Tetsuro; Senda, Hisato; Iwatani, Wakao; Tatsumi, Yoshiyuki; Suda, Masahiro; Arika, Tadashi
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 20 p. 2833 - 2838
反应条件
1: trifluoroacetic acid / dichloromethane / 6 h / -5 - 20 °C 2: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / -5 °C / |Reflux 3: dichloromethane / 0 - 20 °C View Scheme
参考文献
SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu
Patent: WO2013/71697 A1, 2013 ;
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Fukui, Hideto; Shibata, Tetsuo; Naito, Takanobu; Nakano, Jun; Maejima, Tetsuro; Senda, Hisato; Iwatani, Wakao; Tatsumi, Yoshiyuki; Suda, Masahiro; Arika, Tadashi
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 20 p. 2833 - 2838
反应条件
1: 96 percent / TFA / CH2Cl2 2: LiAlH4 / tetrahydrofuran View Scheme
参考文献
Fukui, Hideto; Shibata, Tetsuo; Naito, Takanobu; Nakano, Jun; Maejima, Tetsuro; Senda, Hisato; Iwatani, Wakao; Tatsumi, Yoshiyuki; Suda, Masahiro; Arika, Tadashi
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 20 p. 2833 - 2838
反应条件
1: TFA / CH2Cl2 / 0 - 20 °C 2: 69 percent / LiAlH4 / tetrahydrofuran / 0 - 20 °C View Scheme
参考文献
Hale, Jeffrey J.; Budhu, Richard J.; Mills, Sander G.; MacCoss, Malcolm; Malkowitz, Lorraine; Siciliano, Salvatore; Gould, Sandra L.; DeMartino, Julie A.; Springer, Martin S.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 11 p. 1437 - 1440
