2-乙酰基-1-甲基吡咯合成路线 （共 26 条）
反应条件
1-butylpyridinium tetrafluoroborate; ytterbium(III) triflate T=20°C; Friedel-Crafts reaction; 1.5 h;
参考文献
Su, Weike; Wu, Chunlei; Su, Hao
Journal of Chemical Research, 2005 , # 1 p. 67 - 68
反应条件
zinc trifluoromethanesulfonate in nitromethane T=20°C; Friedel-Crafts acylation; 4 h;
参考文献
He, Fei; Wu, Huayue; Chen, Jiuxi; Su, Weike
Synthetic Communications, 2008 , vol. 38, # 2 p. 255 - 264
反应条件
1: N,N-dimethyl acetamide With bis(trichloromethyl) carbonate in tetrachloromethane T=0°C; 2: 1-methyl-pyrrole in tetrachloromethane T=40 - 50°C; Vilsmeier-Haack reaction; 1 h; 3: With sodium hydroxide in tetrachloromethane
参考文献
Shi; Su; Shan
Journal of the Indian Chemical Society, 2005 , vol. 82, # 11 p. 1019 - 1021
反应条件
1,4-diaza-bicyclo[2.2.2]octane in N,N-dimethyl-formamide T=90 - 92°C; 23 h;
参考文献
Laurila, Michael L.; Magnus, Nicholas A.; Staszak, Michael A.
Organic Process Research and Development, 2009 , vol. 13, # 6 p. 1199 - 1201
反应条件
potassium hydroxide; 18-crown-6 ether in benzene 2 h; Ambient temperature;
参考文献
Goldberg Yu.; Abele; Shymanska
Synthetic Communications, 1991 , vol. 21, # 4 p. 557 - 562
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene 5 h; Heating;
参考文献
Antonio, Yulia; Cruz, Ma. Elizabeth De La; Galeazzi, Edvige; Guzman, Angel; Bray, Brian L.; et al.
Canadian Journal of Chemistry, 1994 , vol. 72, # 1 p. 15 - 22
反应条件
potassium hydroxide; dimethyl sulfoxide T=70°C; P=7355.08 Torr; 3 h;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 27, # 4 p. 363 - 365
Khimiya Geterotsiklicheskikh Soedinenii, , # 4 p. 460 - 463
反应条件
in tetrahydrofuran; hexane T=-70°C; 4 h;
参考文献
Brittain, Judith M.; Jones, R. Alan; Arques, Jose Sepulveda; Saliente, Teresa Aznar
Synthetic Communications, 1982 , vol. 12, # 3 p. 231 - 248
反应条件
1: 96 percent / K2CO3 / dimethylformamide / 16 h / Ambient temperature 2: 92 percent / m-chloroperbenzoic acid / CH2Cl2 / 4 h 3: 64 percent / tri-n-butyltin hydride, azobisisobutyronitrile / benzene / 5 h / Heating View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 72, # 1 p. 15 - 22
反应条件
1: 92 percent / m-chloroperbenzoic acid / CH2Cl2 / 4 h 2: 64 percent / tri-n-butyltin hydride, azobisisobutyronitrile / benzene / 5 h / Heating View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 72, # 1 p. 15 - 22
